Contacts : Romain MARIGNIER, Christine DELPRAT Phone : +33 4 72 68 19 54
email : romain.marignier@chu-lyon.fr , email : christine.delprat@univ-lyon1.fr
Program: this teaching unit, in English, builds on students' basic neurology and immunology knowledge to develop fundamental research concepts in neuro-immunology that have applications in clinical and pharmaceutical research in the field of neuro-inflammatory, neuro-degenerative and neuro-infectious diseases. The topics will be:
1) Cellular and molecular biology of the central nervous system immune responses; definitions of neuro-inflammatory, neurodegenerative and neuro-infectious diseases
2) Immuno-pathological mechanisms, animal models and therapeutic strategies in:
- autoimmune neuro-inflammatory pathologies: multiple sclerosis and related pathologies, myasthenia and pathologies of the neuromuscular junction, dysimmune neuropathies
- neurodegenerative diseases with an inflammatory component: Alzheimer, prion diseases, narcolepsy
- the "emerging fields": the contribution of the immune system in Parkinson's disease, stroke, epilepsy
3) The contribution of the immune system to infectious encephalitis
Speakers:
Pedagogical team of immunology and neurology of the University of Lyon, UFR Biosciences, Faculty of Medicine of Lyon East and South. Conferences on news items will be organized. The speakers will be invited on the basis of their notoriety.
Learning outcomes:
The student gains theoretical and practical insights in inflammatory, infectious and/or autoimmune neuro-immunological disorders with an emphasis on pathogenesis and research development for diagnosis and treatments.
- Neuro-immunology knowledge: the student can describe neuro-infections, immune-mediated neuropathies, neuro-inflammations, has insights in the epidemiology of these diseases, can interpret measures to diagnose or correct these diseases, explain how biological mechanisms cause these diseases and acquire a comprehensive overview of the field.
- Future: the student can discuss recent scientific advances in autoimmunity, infection and inflammation of the central nervous system, analyse and understand the manipulations of various animal models inthis context.
- Practical skills: the student can develop his English proficiency, speed-reading capacities, listening, writing and oral presenting skills, and interactivity in scientific questioning.
(updated on : 2019-04-24)
