Contacts : Christine DELPRAT Tél : 04 72 68 19 54, Virginie DESESTRET
email : christine.delprat@univ-lyon1.fr , email : virginiedesestret@gmail.com
Program: this teaching unit, in English, builds on students' basic neurology and immunology knowledge to develop fundamental research concepts in neuro-immunology that have applications in clinical and pharmaceutical research in the field of oncology and neurology. The topics will be:
1) The nervous system, definition of an immuno-privileged site; migration of immune system cells into the nervous system; role of cerebrospinal fluid in blood / brain exchanges; neuro-immunology detected by the neuropathologist.
2) Interactions between cancer, immune system and nervous system; Anti-tumor immunity and paraneoplastic neurological syndromes
3) Innate neuro-immunity and stress
4) Biotherapies: treatments based on the use of cytokines or antibodies; immuno-targeted therapeutics in neurodegenerative diseases; immunotherapies in multiple sclerosis and related diseases: mechanisms and strategies.
Speakers:
Pedagogical team of immunology and neurology of the University of Lyon, FST-Department of Biology, Faculty of Medicine of Lyon East and South.
Conferences on news items will be organized. The speakers will be invited on the basis of their notoriety.
Learning outcomes:
The student gains theoretical and practical insights in neuro-immunological structures and diseases with an emphasis on pathogenesis and research development for diagnosis and biotherapy treatments.
- Neuro-immunology knowledge: the student can describe central nervous system cells and structure interacting with the immune system and involved in several neuro-immunological diseases, has insights in the epidemiology of these diseases, can interpret measures to diagnose or correct these diseases, explain how biological mechanisms cause these diseases and acquire a comprehensive overview of the field.
- Future: the student can discuss recent scientific advances contributing to the progress of biotherapy treatments, analyse, understand and manipulate interactions between central nervous system and the immune system, specifically related to the context of the immune privilege sites, paraneoplastic disorders and cancers of the central nervous system.
- Practical skills: the student can develop his English proficiency, speed-reading capacities, listening, writing and oral presenting skills, and interactivity in scientific questioning.
(updated on : 2019-04-24)
